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Semarion

semarion

Semarion has been founded by Tarun Vemulkar (c2012) and Jeroen Verheyen (a2014). Tarun and Jeroen won the NanoDTC Translational Prize to jointly develop the technology that led to the formation of Semarion.

Semarion’s mission is to triple the success rate of clinical trials by providing novel in-depth protein fingerprint insight into a patient’s state of health.

Drug development suffers from high failure rates during clinical trial phases 2 (70%) and 3 (50%) which can be overcome by patient stratification and precision medicine. Mass spectroscopy (protein fingerprints) and low-biomarker assays (1-3 proteins) have been used to identify high response patient populations. These technologies are, however, not scalable or give minimal insight. Further, genomic tools cannot provide the same level of insight into a patient’s state of health and disease.

Semarion’s proteomics platform uses novel magnetic nanoparticles with highly tuneable magnetic, optical, and surface properties. This allows the Semarion platform to simultaneously quantify 1,000s of proteins in small samples, in an accurate, affordable, and automated way.

Semarion will provide tools and services to pharma companies and clinical research organisations. Our technology can enable high-level patient stratification while generating additional data on efficacy, toxicity, off-target effects, and new drug targets.

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Admissions for Oct 2020

Sep 03, 2019

We are now accepting applications for Oct 2020 entry. The deadline for the 1st review round is 3 Dec 2019. Some funding applications may be sooner. See www.nanodtc.cam.ac.uk/apply for more information.

Inspiring the next generation of scientists

Aug 09, 2019

Demelza Wright and Taylor Uekert, both cohort 2016 students, have featured in the Inspirational Scientist Video series put together by Cambridge University Press Education.

Call for Mini Project proposals

Jun 19, 2019

The NanoDTC invites Mini Project proposals from Cambridge Academics for its incoming c2019 cohort. Submission deadline is 11th Oct 2019.