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Prof. David Klenerman FRS

Office Phone: 01223-336481


Optical spectroscopy ; Self-Assembly, ; Methodological Development ; NanoSpectroscopy ; Nano-assembly

Key Publications

Ubiquitin chain conformation regulates recognition and activity of interacting proteins. Nature  492, 266-270 (2012).

Direct Observation of the Interconversion of Normal and Toxic Forms of alpha-Synuclein. Cell  149, 1048-1059 (2012).

The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-beta(1-40) peptide. Nature structural & molecular biology 19, 79-83 (2012).

Nanoscale live-cell imaging using hopping probe ion conductance microscopy. Nature Methods 6, 279 - 281 (2009)

Direct characterization of amyloidogenic oligomers by single-molecule fluorescence. Proc. Natl. Acad. Sci. USA 105, 14424-14429 (2008).

Accurate whole human genome sequencing using reversible terminator chemistry. Nature 456, 53-59 (2008).

RSS Feed Latest news

Admissions for Oct 2020

Sep 03, 2019

We are continuing to accept applications for Oct 2020 entry. The deadline for the 2nd review round is 7 Jan 2020. See for more information.

Inspiring the next generation of scientists

Aug 09, 2019

Demelza Wright and Taylor Uekert, both cohort 2016 students, have featured in the Inspirational Scientist Video series put together by Cambridge University Press Education.

Call for Mini Project proposals

Jun 19, 2019

The NanoDTC invites Mini Project proposals from Cambridge Academics for its incoming c2019 cohort. Submission deadline is 11th Oct 2019.