Dr. Amberley Stephens
Amberley is a Senior Research Associate in the Molecular Neuroscience Group. Her research focuses on the interactions of proteins that lead to folding or misfolding. She uses a range of biophysical techniques and microscopy to investigate how the protein alpha-synuclein, involved in Parkinson’s disease, interacts with water molecules, ions, and lipid membranes. These interactions can influence the propensity for alpha-synuclein to misfold and aggregate into pathological amyloid fibrils. She is also interested in bacterial amyloid fibrils which form a key structural component of the extracellular matrix of biofilms. By targeting the bacterial amyloids with anti-amyloid compounds she hopes to identify new antimicrobials to prevent or destroy biofilms.
Her publications can be found here: https://scholar.google.com/citations?hl=en&user=RYnFwCAAAAAJ&view_op=list_works&sortby=pubdate